Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 14/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MT-CO1 | P00395 | 1/20 | 0.51 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985457 | 0.94 | PTGS2 (0.63) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985290 | 0.94 | PTGS2 (0.63) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985509 | 0.94 | PTGS2 (0.49) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985446 | 0.92 | OPRD1 (0.58) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985483 | 0.89 | PTGS2 (0.48) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985377 | 0.85 | PTGS2 (0.46) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985518 | 0.85 | PTGS2 (0.64) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985301 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985467 | 0.81 | MAPK14 (0.60) | PTGS2PTGS1HPGDKDM4EMT-CO1 | |
| SCHEMBL8985304 | 0.81 | PTGS2 (0.55) | PTGS2PTGS1HPGDKDM4EMT-CO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |