SCHEMBL8511154

SCHEMBL8511154

CC(C(=O)O)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.37
TP53 P04637 1/20 0.35
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
MMP1 P03956 2/20 0.32
MMP2 P08253 2/20 0.32
MMP9 P14780 2/20 0.32
MMP8 P22894 2/20 0.32
MMP13 P45452 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933456 0.91 THRB (0.44) THRBTP53CA1CA2MMP1
SCHEMBL8985374 0.91 THRB (0.44) THRBTP53CA1CA2MMP1
SCHEMBL1766346 0.84 TP53 (0.38) TP53
SCHEMBL20856788 0.78 THRB (0.31) THRBCA1CA2MMP1MMP2
SCHEMBL28684999 0.78 THRB (0.32) THRB
SCHEMBL28648873 0.74 TP53 (0.38) TP53
SCHEMBL19863241 0.73 CES1 (0.44)
SCHEMBL8858648 0.73 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL8858644 0.73 THRB (0.41) THRBCA1CA2MMP1MMP2
SCHEMBL1032404 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2643289-B1 PROCESS FOR PRODUCING PERFLUORINATED ORGANIC COMPOUNDS SOLVAY SPECIALTY POLYMERS IT (IT) 2018-01-24 EP disclosed
US-9051259-B2 Process for producing perfluorinated organic compounds SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2015-06-09 US disclosed
EP-2643289-A1 PROCESS FOR PRODUCING PERFLUORINATED ORGANIC COMPOUNDS Solvay Specialty Polymers Italy S.p.A. (IT) 2013-10-02 EP disclosed
US-20130245289-A1 Process for producing perfluorinated organic compounds SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2013-09-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130245289-A1 Process for producing perfluorinated organic compounds PFAS, ADH1A, CYP2F1 THRB 737/4885TP53 1651/4885CA1 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.