Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985195 | 0.84 | PTGS2 (0.47) | PTGS2 | |
| SCHEMBL8985529 | 0.83 | — | — | |
| SCHEMBL8985332 | 0.83 | PTGS1 (0.43) | PTGS2 | |
| SCHEMBL8985322 | 0.82 | PTGS2 (0.33) | PGRNR3C1NR3C2ARPTGS2 | |
| SCHEMBL8985255 | 0.80 | MAPK14 (0.45) | PTGS2 | |
| SCHEMBL8985372 | 0.79 | PTGS2 (0.34) | PGRNR3C1NR3C2ARPTGS2 | |
| SCHEMBL8985497 | 0.78 | APP (0.35) | PGRNR3C1NR3C2ARPTGS2 | |
| SCHEMBL9207743 | 0.69 | PTGS2 (0.46) | NR3C2PTGS2 | |
| SCHEMBL8985262 | 0.68 | PTGS2 (0.65) | PTGS2 | |
| SCHEMBL8985472 | 0.64 | AURKA (0.48) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |
| WO-1991019708-A1 | NEW THIOPHENE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-26 | — | — | WO | disclosed |