Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.57 |
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.55 |
| ▸ | F2 | P00734 | 3/20 | 0.50 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.49 |
| ▸ | HPD | P32754 | 1/20 | 0.47 |
| ▸ | MLYCD | O95822 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985645 | 0.80 | MAOB (0.58) | MAOBMAOANR4A2SMPD1HPD | |
| SCHEMBL5605085 | 0.74 | MAOB (0.68) | MAOBMAOANR4A2SMPD1HPD | |
| SCHEMBL1436284 | 0.73 | MAOB (1.00) | MAOBMAOANR4A2SMPD1RXRA | |
| SCHEMBL15389210 | 0.73 | MLYCD (0.68) | MLYCD | |
| SCHEMBL27916079 | 0.72 | NR4A2 (0.74) | MAOBMAOANR4A2F2SMPD1 | |
| SCHEMBL7052037 | 0.72 | NR4A2 (1.00) | MAOBMAOANR4A2SMPD1HPD | |
| SCHEMBL9272104 | 0.72 | BCHE (0.60) | MAOBMAOANR4A2HPD | |
| SCHEMBL8985602 | 0.71 | MEN1 (0.48) | MAOBMAOANR4A2 | |
| Hydrochloric Acid SCHEMBL8985560 | 0.71 | MEN1 (0.48) | MAOBMAOANR4A2 | |
| SCHEMBL8985631 | 0.71 | MAOB (0.58) | MAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |