Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 10/20 | 1.00 |
| ▸ | MAOA | P21397 | 1/20 | 0.76 |
| ▸ | MAOB | P27338 | 1/20 | 0.76 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.74 |
| ▸ | RXRA | P19793 | 1/20 | 0.74 |
| ▸ | RXRB | P28702 | 1/20 | 0.74 |
| ▸ | RXRG | P48443 | 1/20 | 0.74 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.68 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.68 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.67 |
| ▸ | PPARA | Q07869 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30994900 | 0.88 | NR4A2 (0.82) | NR4A2MAOBMRGPRX4RXRARXRB | |
| SCHEMBL27815839 | 0.88 | NR4A2 (0.82) | NR4A2MAOBMRGPRX4RXRARXRB | |
| SCHEMBL30207018 | 0.87 | NR4A2 (1.00) | NR4A2MAOBMRGPRX4NR4A1NR4A3 | |
| SCHEMBL339009 | 0.87 | NR4A2 (1.00) | NR4A2MAOBMRGPRX4NR4A1NR4A3 | |
| SCHEMBL1436284 | 0.87 | MAOB (1.00) | NR4A2MAOAMAOBRXRARXRB | |
| SCHEMBL13802461 | 0.87 | NR4A2 (1.00) | NR4A2MAOAMAOBMRGPRX4RXRA | |
| SCHEMBL4638741 | 0.87 | NR4A2 (0.76) | NR4A2MAOAMAOBMRGPRX4RXRA | |
| SCHEMBL29784229 | 0.87 | NR4A2 (1.00) | NR4A2MAOAMAOBMRGPRX4RXRA | |
| SCHEMBL1123155 | 0.86 | NR4A2 (0.91) | NR4A2MAOBMRGPRX4NR4A1NR4A3 | |
| Hydrochloric Acid SCHEMBL4748074 | 0.86 | NR4A2 (0.97) | NR4A2MAOBMRGPRX4NR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191323-A1 | Hypoglycemic agent | AJINOMOTO CO., INC. (JP) | 2003-10-09 | — | — | US | disclosed |
| US-20030162818-A1 | Acylsulfonamide derivative | AJINOMOTO CO. INC. (JP) | 2003-08-28 | — | — | US | disclosed |
| US-6555584-B1 | Acetyl-coa carboxylase inhibitors | AJINOMOTO CO., INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1300142-A1 | HYPOGLYCEMICS | Ajinomoto Co., Inc. (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162818-A1 | Acylsulfonamide derivative | ACSS2, ACACA, FASN | NR4A2 2332/4885MAOA 591/4885MAOB 396/4885 |
| US-20030191323-A1 | Hypoglycemic agent | GPR119, IAPP, SLC5A2 | NR4A2 3157/4885MAOA 2901/4885MAOB 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.