Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 4/20 | 0.47 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.45 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8985560 | 1.00 | MEN1 (0.48) | MEN1MAPK1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL20314090 | 0.90 | MEN1 (0.46) | MEN1MAPK1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL20314093 | 0.89 | MEN1 (0.45) | MEN1MAPK1HTTKMT2ASMN1; SMN2 | |
| Maleic Acid SCHEMBL8985703 | 0.87 | NR4A2 (0.47) | KMT2AMAOAMAOBACHENR4A2 | |
| Fumaric Acid SCHEMBL8985706 | 0.87 | NR4A2 (0.47) | KMT2AMAOAMAOBACHENR4A2 | |
| SCHEMBL8985608 | 0.86 | MAOB (0.51) | MAOAMAOBACHENR4A2CCR5 | |
| SCHEMBL9272104 | 0.86 | BCHE (0.60) | MEN1MAPK1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL9115916 | 0.84 | MAOB (0.50) | MEN1MAPK1HTTKMT2ASMN1; SMN2 | |
| Oxalic Acid SCHEMBL8985649 | 0.80 | HRH3 (0.52) | SMN1; SMN2MAOAMAOBNR4A2 | |
| SCHEMBL12993155 | 0.79 | PYCR1 (0.56) | ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |