Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 9/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.47 |
| ▸ | FOXM1 | Q08050 | 1/20 | 0.45 |
| ▸ | LSS | P48449 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL8985649 | 0.93 | HRH3 (0.52) | MAOBMAOANR4A2 | |
| Hydrochloric Acid SCHEMBL8985560 | 0.86 | MEN1 (0.48) | MAOBMAOANR4A2CCR5ACHE | |
| SCHEMBL8985602 | 0.86 | MEN1 (0.48) | MAOBMAOANR4A2CCR5ACHE | |
| SCHEMBL9116935 | 0.81 | MAOB (0.53) | MAOBAPPMAOAFOXM1NR4A2 | |
| SCHEMBL8985627 | 0.79 | CARM1 (0.68) | CCR5 | |
| SCHEMBL8985631 | 0.78 | MAOB (0.58) | MAOBMAOANR4A2 | |
| SCHEMBL20314090 | 0.75 | MEN1 (0.46) | MAOBMAOANR4A2CCR5ACHE | |
| SCHEMBL20314093 | 0.74 | MEN1 (0.45) | MAOBMAOALSSNR4A2ACHE | |
| SCHEMBL10991891 | 0.74 | MAOB (0.80) | MAOBAPPMAOANR4A2 | |
| Maleic Acid SCHEMBL8985703 | 0.74 | NR4A2 (0.47) | MAOBMAOANR4A2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | claimed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |