Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.49 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12265182 | 0.86 | TSHR (0.47) | OPRK1OPRM1OPRD1AOC3BCHE | |
| Hydrochloric Acid SCHEMBL31094860 | 0.85 | ALDH1A1 (0.48) | OPRK1OPRM1OPRD1BCHEALDH1A1 | |
| SCHEMBL231061 | 0.79 | OPRK1 (0.63) | OPRK1OPRM1OPRD1AOC3BCHE | |
| SCHEMBL14047033 | 0.79 | OPRK1 (0.69) | OPRK1OPRM1OPRD1AOC3BCHE | |
| SCHEMBL13049987 | 0.77 | OPRK1 (0.67) | OPRK1OPRM1OPRD1AOC3BCHE | |
| SCHEMBL12049809 | 0.77 | OPRK1 (0.61) | OPRK1OPRM1OPRD1AOC3BCHE | |
| SCHEMBL8936121 | 0.77 | MAOB (0.47) | OPRK1AOC3ALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL20135644 | 0.77 | MEN1 (0.45) | — | |
| SCHEMBL20135643 | 0.77 | MEN1 (0.45) | — | |
| SCHEMBL8936116 | 0.77 | MAOB (0.47) | OPRK1AOC3ALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583000-A | DETECTING PRESENCE OF RETROVIRAL PROTEASES IN SAMPLE BY COMBINING WITH SPECIFIED COMPOUND AND DETECTING PRESENCE OF COMPLEXES FORMED | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1996-12-10 | — | — | US | disclosed |