SCHEMBL2861284

SCHEMBL2861284

Cc1cc(O)cc(-c2ccccc2)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.62
BACE1 P56817 3/20 0.58
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MEN1 O00255 1/20 0.50
MAPT P10636 1/20 0.50
MPI P34949 1/20 0.50
KMT2A Q03164 1/20 0.50
ALOX5 P09917 2/20 0.47
PDE4B Q07343 1/20 0.43
PTPN1 P18031 1/20 0.43
TTR P02766 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
PELI1 Q96FA3 1/20 0.42
BCL2L1 Q07817 1/20 0.41
HSD17B10 Q99714 1/20 0.41
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31028131 0.85 CA1 (0.54) ESR2BACE1ALDH1A1HPGDALOX5
SCHEMBL172874 0.85 CA1 (0.54) ESR2BACE1ALDH1A1HPGDALOX5
SCHEMBL1535921 0.84 BACE1 (0.68) ESR2BACE1ALDH1A1HPGDKDM4E
SCHEMBL30693664 0.83 ESR2 (0.62) ESR2BACE1ALDH1A1HPGDKDM4E
SCHEMBL8986922 0.83 ESR2 (0.52) ESR2BACE1ALDH1A1HPGDKDM4E
SCHEMBL8337717 0.83 ESR2 (0.62) ESR2BACE1ALDH1A1HPGDKDM4E
SCHEMBL23940773 0.82 ESR2 (0.60) ESR2BACE1ALDH1A1HPGDKDM4E
SCHEMBL510022 0.81 ESR2 (0.55) ESR2BACE1ALDH1A1MEN1MAPT
SCHEMBL27734232 0.81 ESR2 (0.53) ESR2BACE1ALDH1A1HPGDALOX5
SCHEMBL28926510 0.80 ESR2 (0.57) ESR2BACE1ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-7615650-B2 Process for producing chroman compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-11-10 US disclosed
CN-100364160-C Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES (JP) 2008-01-23 CN disclosed
US-20070179304-A1 Process for producing chroman compound MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2007-08-02 US disclosed
EP-1710239-A1 PROCESS FOR PRODUCING CHROMAN COMPOUND MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2006-10-11 EP disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed
US-4612362-A Thermotropic polyester-carbonates containing 2,2-dimethyl-1,3-propanediol ALLIED CORPORATION (US) 1986-09-16 US disclosed
US-4398018-A Temperature stable thermotropic poly(ester carbonate) derived from t-butylhydroquinone ALLIED CORPORATION (US) 1983-08-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070179304-A1 Process for producing chroman compound TAF9, TAF1, CHD1 ESR2 2397/4885BACE1 2059/4885ALDH1A1 306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.