Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27651965 | 0.86 | ESR1 (0.43) | ACHECYP3A4HSD17B10TDP1TAAR1 | |
| SCHEMBL28158641 | 0.83 | ACHE (0.42) | ACHEALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL21537440 | 0.82 | ACHE (0.57) | ACHECYP3A4HSD17B10TDP1TAAR1 | |
| SCHEMBL29400302 | 0.79 | ACHE (0.63) | ACHECYP3A4HSD17B10TDP1TAAR1 | |
| SCHEMBL535035 | 0.79 | ACHE (0.63) | ACHECYP3A4HSD17B10TDP1TAAR1 | |
| SCHEMBL11221664 | 0.78 | KDM4E (0.41) | ACHECYP3A4HSD17B10TDP1ALDH1A1 | |
| SCHEMBL4557173 | 0.77 | TDP1 (0.62) | ACHECYP3A4HSD17B10TDP1TAAR1 | |
| SCHEMBL11219415 | 0.76 | PTGS2 (0.38) | ACHEALDH1A1TP53MEN1KMT2A | |
| SCHEMBL8986931 | 0.76 | MEN1 (0.46) | CYP3A4TDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL13310879 | 0.76 | CYP3A4 (0.78) | ACHECYP3A4HSD17B10TDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482822-A | MULTILAYER ELEMENT FOR OPTICAL DISKS WITH SUBSTRATE AND OPTICAL COATINGS | CANON KABUSHIKI KAISHA (JP) | 1996-01-09 | — | — | US | disclosed |