SCHEMBL28158641

SCHEMBL28158641

Cc1ccc(-c2c(-c3ccc(C)cc3)c(-c3ccc(C)cc3)c3c(N)c4ccccc4c(N)c3c2-c2ccc(C)cc2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 3/20 0.42
ADORA2A P29274 1/20 0.42
PTGS2 P35354 3/20 0.42
CYP1A1 P04798 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP1B1 Q16678 1/20 0.41
GSK3B P49841 1/20 0.41
ADK P55263 1/20 0.41
PDE9A O76083 1/20 0.40
PDE1C Q14123 1/20 0.40
CTSV O60911 1/20 0.38
CTSL P07711 1/20 0.38
HPGD P15428 1/20 0.38
RAB9A P51151 1/20 0.38
MAPT P10636 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
ALDH1A1 P00352 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11219415 0.91 PTGS2 (0.38) ACHEADORA2APTGS2CYP1A1CYP1A2
SCHEMBL8986934 0.83 ACHE (0.48) ACHEHPGDRAB9AMAPTMEN1
SCHEMBL27651965 0.83 ESR1 (0.43) ACHECYP1A2GSK3BHPGDRAB9A
SCHEMBL4249048 0.79 ADORA2A (0.40) ACHEADORA2APTGS2CYP1A1CYP1A2
SCHEMBL29444809 0.79 ADORA2A (0.40) ACHEADORA2APTGS2CYP1A1CYP1A2
SCHEMBL18338751 0.78 GPR84 (0.36) ACHEADORA2APTGS2CYP1A1CYP1A2
SCHEMBL3722164 0.76 ACHE (0.48) ACHEADORA2APTGS2CYP1A1CYP1A2
SCHEMBL27888667 0.76 NPC1 (0.39) ACHEADORA2ACYP1A1CYP1A2CYP1B1
SCHEMBL30742831 0.75 ACHE (0.57) ACHEADORA2APTGS2GSK3BADK
SCHEMBL3477351 0.75 ACHE (0.57) ACHEADORA2APTGS2GSK3BADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110049990-A polycyclic aromatic amino compound 学校法人关西学院 2019-07-23 CN disclosed
CN-105658606-B Anthracene based compound, luminescent layer material, use its organic electroluminescent device, display device and lighting device 捷恩智株式会社 2018-01-09 CN disclosed
CN-107531641-A Oxazoline ring-containing compound, material for electron transport/injection layer containing the same, and organic electroluminescent element using the same 捷恩智株式会社 2018-01-02 CN disclosed
CN-103328420-B Anthracene compound and use its organic electroluminescent element, luminescent layer material, display device and lighting device 捷恩智株式会社 2017-08-11 CN disclosed
CN-106905367-A Polycyclc aromatic compound, polymer and its manufacture method and its application 学校法人关西学院 2017-06-30 CN disclosed