Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CTSV | O60911 | 1/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.48 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.48 |
| ▸ | GUSB | P08236 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28132752 | 0.84 | MEN1 (0.60) | SMN1; SMN2HPGDMAPK1HTTPOLB | |
| SCHEMBL1173520 | 0.80 | HPGD (1.00) | SMN1; SMN2HPGDMAPK1HTTCTSV | |
| SCHEMBL28133652 | 0.80 | HPGD (1.00) | SMN1; SMN2HPGDMAPK1HTTCTSV | |
| SCHEMBL29612166 | 0.80 | HPGD (1.00) | SMN1; SMN2HPGDMAPK1HTTCTSV | |
| Carbazole SCHEMBL27552113 | 0.78 | CTSV (0.67) | SMN1; SMN2HPGDHTTPOLBCTSV | |
| SCHEMBL14406226 | 0.78 | ELANE (0.61) | SMN1; SMN2MAPK1POLBALDH1A1ELANE | |
| SCHEMBL28060912 | 0.78 | IDO1 (0.64) | SMN1; SMN2POLBCTSVCTSLPARP1 | |
| SCHEMBL9263322 | 0.78 | CTSV (0.51) | SMN1; SMN2POLBCTSVCTSLPARP1 | |
| SCHEMBL31456152 | 0.78 | IDO1 (0.64) | SMN1; SMN2POLBCTSVCTSLPARP1 | |
| SCHEMBL8986955 | 0.78 | HPGD (0.74) | SMN1; SMN2HPGDMAPK1HTTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |