Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 14/20 | 0.57 |
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | FABP4 | P15090 | 1/20 | 0.50 |
| ▸ | PTGIR | P43119 | 3/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.43 |
| ▸ | RXRB | P28702 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | FABP1 | P07148 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9291667 | 1.00 | LTB4R (0.57) | LTB4RFABP3FABP4PTGIRRXRA | |
| SCHEMBL8987144 | 1.00 | LTB4R (0.57) | LTB4RFABP3FABP4PTGIRRXRA | |
| SCHEMBL8987118 | 0.89 | LTB4R (0.57) | LTB4RFABP3FABP4RXRARXRB | |
| SCHEMBL8987233 | 0.88 | LTB4R (0.54) | LTB4R | |
| SCHEMBL8987182 | 0.87 | LTB4R (0.52) | LTB4R | |
| SCHEMBL8987198 | 0.86 | FAAH (0.51) | LTB4R | |
| SCHEMBL3571567 | 0.83 | PTGIR (0.50) | LTB4RFABP3FABP4PTGIRRXRA | |
| SCHEMBL8987151 | 0.81 | PTGIR (0.41) | LTB4RFABP3FABP4PTGIRRXRA | |
| Bicarbonate SCHEMBL3917634 | 0.80 | ADORA1 (0.39) | LTB4RPTGIR | |
| SCHEMBL5407468 | 0.80 | LTB4R (0.62) | LTB4RFABP3FABP4PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0718682-A1 | Silver halide photographic emulsions prepared and sensitized in the presence of sulfodihydroxy aryl compounds | EASTMAN KODAK COMPANY (US) | 1996-06-26 | — | — | EP | disclosed |
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |
| EP-0540604-A1 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | Aventis Pharma S.A. (FR) | 1993-05-12 | — | — | EP | disclosed |
| WO-1992001675-A2 | SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | RHONE-POULENC RORER S.A. (FR) | 1992-02-06 | — | — | WO | disclosed |