Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987122 | 0.87 | ALDH2 (0.46) | LTB4RKMT2AGAAPTGS2TBXAS1 | |
| SCHEMBL8987144 | 0.87 | LTB4R (0.57) | LTB4R | |
| SCHEMBL8986957 | 0.87 | LTB4R (0.57) | LTB4R | |
| SCHEMBL9291667 | 0.87 | LTB4R (0.57) | LTB4R | |
| SCHEMBL8987118 | 0.86 | LTB4R (0.57) | LTB4RTBXAS1 | |
| SCHEMBL8987130 | 0.82 | LTB4R (0.58) | LTB4RFFAR1PPARGPPARDPPARA | |
| SCHEMBL9291603 | 0.82 | LTB4R (0.58) | LTB4RFFAR1PPARGPPARDPPARA | |
| SCHEMBL8987233 | 0.80 | LTB4R (0.54) | LTB4RPPARGPPARAALDH1A1 | |
| SCHEMBL8987198 | 0.76 | FAAH (0.51) | LTB4RGAATBXAS1ALDH1A1 | |
| SCHEMBL1801957 | 0.75 | PPARA (0.68) | LTB4RFFAR1PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |