SCHEMBL898708

SCHEMBL898708

COC(=O)c1ccc(C(=O)OC)c2c1C1CCCCC21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.53
KDM4E B2RXH2 7/20 0.53
HSD17B10 Q99714 3/20 0.51
HPGD P15428 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TSHR P16473 3/20 0.48
RECQL P46063 1/20 0.47
LMNA P02545 1/20 0.46
RIPK1 Q13546 1/20 0.45
CFTR P13569 1/20 0.44
POLB P06746 2/20 0.43
YAP1 P46937 1/20 0.43
GAA P10253 1/20 0.43
ALOX12 P18054 1/20 0.43
KMT2A Q03164 1/20 0.43
NPC1 O15118 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ATM Q13315 1/20 0.43
STS P08842 1/20 0.43
CA12 O43570 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11566905 0.83 KDM4E (0.50) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL5951054 0.80 CA12 (0.46) ALDH1A1KDM4EHSD17B10HPGDNPSR1
Dimethyl Phthalate SCHEMBL28758705 0.76 ALDH1A1 (0.58) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL668829 0.75 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDPOLBGAA
SCHEMBL14823391 0.74 ALDH1A1 (0.54) ALDH1A1KDM4EHPGDTSHRLMNA
SCHEMBL7598114 0.73 KDM4E (0.55) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL19335455 0.73 KDM4E (0.70) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL8834684 0.73 YAP1 (0.53) ALDH1A1KDM4ETSHRRIPK1POLB
SCHEMBL18594835 0.73 KDM4E (0.70) ALDH1A1KDM4EHSD17B10HPGDNPSR1
SCHEMBL7065164 0.73 KDM4E (0.70) ALDH1A1KDM4EHSD17B10HPGDNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11219303-B2 Brush product and method for the production thereof TRISA HOLDING AG (CH) 2022-01-11 US claimed
US-20190159581-A1 BRUSH PRODUCT AND METHOD FOR THE PRODUCTION THEREOF TRISA HOLDING AG (CH) 2019-05-30 US claimed
US-8883279-B2 Fluid-assisted injection molded articles and process TICONA LLC (US) 2014-11-11 US claimed
EP-2685951-A1 ACQUISITION SYSTEM FOR AN ABSORBENT ARTICLE COMPRISING A FLUID PERMEABLE STRUCTURED FIBROUS WEB The Procter and Gamble Company (US) 2014-01-22 EP claimed
EP-2685952-A1 FLUID PERMEABLE STRUCTURED FIBROUS WEB The Procter and Gamble Company (US) 2014-01-22 EP claimed
EP-2686024-A1 STRUCTURED FIBROUS WEB The Procter and Gamble Company (US) 2014-01-22 EP claimed
EP-2686023-A1 STRUCTURED FIBROUS WEB The Procter and Gamble Company (US) 2014-01-22 EP claimed
US-20130327437-A1 HIGH TEMPERATURE CONDUIT HAVING A COMPLEX, THREE-DIMENSIONAL CONFIGURATION TICONA LLC 2013-12-12 US claimed
EP-2655846-A1 HIGH TEMPERATURE CONDUIT HAVING A COMPLEX, THREE-DIMENSIONAL CONFIGURATION Ticona LLC (US) 2013-10-30 EP claimed
WO-2012161840-A1 FLUID PERMEABLE STRUCTURED FIBROUS WEB THE PROCTER & GAMBLE COMPANY (US) 2012-11-29 WO claimed
US-20120238981-A1 Fluid Permeable Structured Fibrous Web PROCTER & GAMBLE COMPANY, THE 2012-09-20 US claimed
US-20120238978-A1 Fluid Permeable Structured Fibrous Web PROCTER & GAMBLE COMPANY, THE 2012-09-20 US claimed
US-20120238982-A1 Structured Fibrous Web PROCTER & GAMBLE COMPANY, THE 2012-09-20 US claimed
WO-2012088378-A1 HIGH TEMPERATUE CONDUIT HAVING A COMPLEX, THREE-DIMESNIONAL CONFIGURATION TICONA LLC (US) 2012-06-28 WO claimed
US-20120082811-A1 Fluid-Assisted Injection Molded Articles and Process TICONA LLC (US) 2012-04-05 US claimed
WO-2012044362-A1 FLUID-ASSISTED INJECTION MOLDED ARTICLES AND PROCESS TICONA LLC (US) 2012-04-05 WO claimed
WO-2010027351-A1 FLUID-ASSISTED INJECTION MOLDED ARTICLES AND PROCESS TICONA, LLC. (US) 2010-03-11 WO claimed
WO-2007103627-A2 SPLITTABLE MULTICOMPONENT FIBER WITH HIGH TEMPERATURE, CORROSION RESISTANT POLYMER FIBER INNOVATION TECHNOLOGY, INC. (US) 2007-09-13 WO claimed
US-20070207317-A1 Splittable multicomponent fiber with high temperature, corrosion resistant polymer FIBER INNOVATION TECHNOLOGY, INC. 2007-09-06 US claimed
US-4550051-A EPOXY RESIN IMPREGNATED GLASS FIBERS EXTERIOR PLIES AND TEXTILE OROR THERMO = PLASTIC CORE DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) 1985-10-29 US claimed