Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | YAP1 | P46937 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951054 | 0.90 | CA12 (0.46) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL17065508 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL898708 | 0.83 | ALDH1A1 (0.53) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL28721789 | 0.81 | ACMSD (0.55) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL28974065 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL30009936 | 0.78 | CXCR5 (0.50) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL30425639 | 0.78 | PTGER4 (0.44) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL1793340 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL20503220 | 0.77 | ACMSD (0.48) | KDM4EALDH1A1HSD17B10HPGDNPSR1 | |
| SCHEMBL30281107 | 0.77 | KDM4E (0.45) | KDM4EALDH1A1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4163860-A | ESTER INTERCHANGE WITH METHANOL OF BIS-DIOL TEREPHTHALATE INTERMEDIATE | RHONE-POULENC-TEXTILE (FR) | 1979-08-07 | — | — | US | claimed |