SCHEMBL8987283

SCHEMBL8987283

COc1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.74
CYP1B1 Q16678 2/20 0.74
CYP1A2 P05177 1/20 0.74
CYP2E1 P05181 1/20 0.74
CYP3A4 P08684 1/20 0.74
CYP2C8 P10632 1/20 0.74
CYP2D6 P10635 1/20 0.74
CYP2A6 P11509 1/20 0.74
CYP2C9 P11712 1/20 0.74
CYP4B1 P13584 1/20 0.74
CYP2B6 P20813 1/20 0.74
CYP3A5 P20815 1/20 0.74
CYP2A7 P20853 1/20 0.74
CYP3A7 P24462 1/20 0.74
CYP2F1 P24903 1/20 0.74
CYP2C18 P33260 1/20 0.74
CYP2C19 P33261 1/20 0.74
CYP2J2 P51589 1/20 0.74
CYP4F2 P78329 1/20 0.74
CYP4F8 P98187 1/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26498639 0.95 CYP1A1 (0.83) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL26498789 0.95 CYP1A1 (0.83) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL26498734 0.95 CYP1A1 (0.83) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL2407878 0.95 CYP1A1 (0.74) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL28102064 0.89 CYP1A2 (0.72) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL28102062 0.88 ABL1 (0.73) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL7241617 0.87 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL29698794 0.87 CYP1A1 (0.57) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL23743214 0.85 CYP1A1 (1.00) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4
SCHEMBL2545199 0.85 ABCB1 (0.62) CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0213893-B1 Photopolymerisable compositions containing substituted pyrylium salts as photoinitiators; and novel pyrylium salts for use therein LOCTITE IRELAND LTD (IE) 1993-11-10 EP claimed
US-11858952-B2 Compound and color conversion film comprising same LG CHEM, LTD. (KR) 2024-01-02 US disclosed
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME LG CHEM, LTD. (KR) 2021-11-11 US disclosed
CN-1802374-A White-emitting compounds, process for the production thereof, and white-emitting devices HIROSE ENGINEERING CO LTD (JP) 2006-07-12 CN disclosed
US-5492915-A ANTIINFLAMMATORY AGENTS RHONE-POULENC RORER S.A. (FR) 1996-02-20 US disclosed
US-5366982-A Antiinflammatory agents or antihistamines RHONE-POULENC RORER S.A. (FR) 1994-11-22 US disclosed
EP-0559742-A1 HERBICIDAL OXAZINE ETHERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-09-15 EP disclosed
EP-0540604-A1 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS Aventis Pharma S.A. (FR) 1993-05-12 EP disclosed
WO-1992001675-A2 SUBSTITUTED BICYCLIC BIS-ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY, THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS RHONE-POULENC RORER S.A. (FR) 1992-02-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210347790-A1 COMPOUND AND COLOR CONVERSION FILM COMPRISING SAME BLVRB, CDYL, CRY1 CYP1A1 651/4885CYP1B1 309/4885CYP1A2 477/4885
US-11858952-B2 Compound and color conversion film comprising same BLVRB, CDYL, CRY1 CYP1A1 651/4885CYP1B1 309/4885CYP1A2 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.