Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 15/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987417 | 0.82 | PTGIR (0.50) | LTB4RPTGESNTRK1 | |
| SCHEMBL8987281 | 0.82 | PTGIR (0.50) | LTB4RPTGESNTRK1 | |
| Bicarbonate SCHEMBL3919502 | 0.80 | PTGES (0.41) | PTGESNTRK1 | |
| SCHEMBL8987348 | 0.80 | PTGES (0.45) | PTGESNTRK1 | |
| SCHEMBL8987043 | 0.78 | FAAH (0.48) | PTGES | |
| SCHEMBL8987239 | 0.78 | FAAH (0.48) | PTGES | |
| SCHEMBL8987067 | 0.78 | FAAH (0.48) | PTGES | |
| SCHEMBL3282641 | 0.78 | PTGES (0.41) | PTGESNTRK1 | |
| SCHEMBL3282637 | 0.78 | PTGES (0.41) | PTGESNTRK1 | |
| SCHEMBL3282547 | 0.76 | HDAC3 (0.37) | PTGESNTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |