Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987417 | 1.00 | PTGIR (0.50) | PTGIRPTGESLTB4RHDAC3PTK2 | |
| SCHEMBL8987348 | 0.89 | PTGES (0.45) | PTGIRPTGESHDAC3HDAC1HDAC2 | |
| SCHEMBL8987239 | 0.85 | FAAH (0.48) | PTGESALDH1A1PTGS2 | |
| SCHEMBL8987043 | 0.85 | FAAH (0.48) | PTGESALDH1A1PTGS2 | |
| SCHEMBL8987067 | 0.85 | FAAH (0.48) | PTGESALDH1A1PTGS2 | |
| SCHEMBL3282641 | 0.82 | PTGES (0.41) | PTGESHDAC3HDAC1HDAC2HDAC8 | |
| Bicarbonate SCHEMBL3919502 | 0.82 | PTGES (0.41) | PTGESALDH1A1NTRK1ADORA2AADORA1 | |
| SCHEMBL8987398 | 0.82 | LTB4R (0.47) | PTGESLTB4RNTRK1 | |
| SCHEMBL3282637 | 0.82 | PTGES (0.41) | PTGESHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3282561 | 0.80 | L3MBTL1 (0.42) | PTGESALDH1A1NTRK1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492915-A | ANTIINFLAMMATORY AGENTS | RHONE-POULENC RORER S.A. (FR) | 1996-02-20 | — | — | US | disclosed |
| US-5366982-A | Antiinflammatory agents or antihistamines | RHONE-POULENC RORER S.A. (FR) | 1994-11-22 | — | — | US | disclosed |