Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 6/20 | 0.54 |
| ▸ | MMP2 | P08253 | 5/20 | 0.54 |
| ▸ | MMP9 | P14780 | 5/20 | 0.54 |
| ▸ | MMP8 | P22894 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987618 | 0.91 | MMP2 (0.59) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL8987554 | 0.90 | MMP13 (0.49) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL8987678 | 0.89 | MMP2 (0.52) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL7468975 | 0.84 | MAPT (0.44) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL8987569 | 0.83 | MAPT (0.53) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL7469008 | 0.83 | MAPT (0.50) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL7468134 | 0.80 | MAPT (0.49) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL8987549 | 0.80 | MAPT (0.49) | MMP13MMP2MMP9MMP8MEN1 | |
| SCHEMBL7467562 | 0.79 | MAPT (0.44) | MMP13MMP2MMP9MMP8MEN1 | |
| Hydrochloric Acid SCHEMBL8987608 | 0.79 | MAPT (0.48) | MMP13MMP2MMP9MMP8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719765-A2 | Phenylbenzimidazole derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-07-03 | — | — | EP | disclosed |