Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023017 | 0.87 | KDM4E (0.56) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8987638 | 0.81 | KDM4E (0.61) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL8987687 | 0.78 | KDM4E (0.58) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9298894 | 0.76 | ALDH1A1 (0.56) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL9299629 | 0.76 | FEN1 (0.57) | KMT2ARXFP1MPOXDH | |
| SCHEMBL6804934 | 0.74 | CYP1A2 (0.65) | KDM4EALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL17241565 | 0.74 | KDM4E (0.81) | KDM4EALDH1A1SMN1; SMN2MAPTHPGD | |
| SCHEMBL18708215 | 0.69 | ALDH1A1 (1.00) | ALDH1A1MAPTHSD17B10MAPK1LMNA | |
| SCHEMBL6300064 | 0.68 | MPO (0.70) | ALDH1A1MAPTHSD17B10POLBMAPK1 | |
| SCHEMBL15537894 | 0.68 | ALDH1A1 (0.73) | ALDH1A1MAPTHSD17B10POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454060-B1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | DROESSLER KARL PROF DR (DE) | 1996-07-03 | — | — | EP | disclosed |
| US-5306721-A | Immunostimulants, viricides | ARZNEIMITTELERK DRESDEN G.M.B.H. (DE) | 1994-04-26 | — | — | US | disclosed |
| EP-0454060-A1 | 3-(Mercaptoalkyl)-quinazoline-2,4(1H,3H)-diones, processes for their preparation, and pharmaceutical compositions | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-10-30 | — | — | EP | disclosed |