SCHEMBL8987724

SCHEMBL8987724

C=C(CC)C(=O)OOCCOCCC#N

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8887084 0.82 THRB (0.47) ALDH1A1TSHRTHRB
SCHEMBL28405643 0.82 THRB (0.35) TSHRTHRB
SCHEMBL111959 0.80 THRB (0.48) ALDH1A1TSHRTHRB
SCHEMBL8024320 0.74 THRB (0.41) ALDH1A1TSHRTHRB
SCHEMBL4409839 0.74
SCHEMBL31411915 0.72 THRB (0.35) THRB
SCHEMBL15284312 0.71 ALDH1A1 (0.44) ALDH1A1TSHRTHRB
SCHEMBL14335765 0.71 TSHR (0.40) ALDH1A1TSHR
SCHEMBL301507 0.70 THRB (0.59) ALDH1A1TSHRTHRB
SCHEMBL8698549 0.70 THRB (0.59) ALDH1A1TSHRTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5512647-A CYANO GROUP-CONTAINING ACRYLATES, UNSATURATED NITRILES AND OTHER ETHYLENICALLY UNSATURATED MONOMERS; FUEL OIL AND COLD RESISTANCE TOSOH CORPORATION (JP) 1996-04-30 US disclosed