Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987725 | 0.96 | CDK5 (0.46) | CDK2CCNA2CCNA1LTA4HEPHX2 | |
| SCHEMBL8987824 | 0.89 | KMT2A (0.50) | CDK2CCNA2CCNA1LTA4HEPHX2 | |
| SCHEMBL8987987 | 0.88 | RIOK2 (0.47) | CDK2CCNA2CCNA1LTA4HEPHX2 | |
| SCHEMBL8987780 | 0.84 | RIOK2 (0.46) | CDK2CCNA2CCNA1LTA4HEPHX2 | |
| SCHEMBL8987786 | 0.83 | CACNA1I (0.50) | CDK2CCNA2CCNA1P2RX7ALDH1A1 | |
| SCHEMBL8987749 | 0.83 | LTA4H (0.46) | LTA4HEPHX2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL8987841 | 0.81 | MAPK14 (0.50) | LTA4HEPHX2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL8987866 | 0.81 | ALDH1A1 (0.46) | LTA4HEPHX2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL8987613 | 0.80 | ANO1 (0.47) | LTA4HEPHX2ALDH1A1MAPK10SMN1; SMN2 | |
| SCHEMBL8988002 | 0.80 | MAPK14 (0.49) | LTA4HEPHX2ALDH1A1MAPK10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |