SCHEMBL8988002

SCHEMBL8988002

CSc1nccc(NC(=O)Cc2ccc(Oc3ccc(F)cc3)cc2)n1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 10/20 0.49
ALDH1A1 P00352 1/20 0.46
MAPK10 P53779 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
WNT3A P56704 1/20 0.45
GSK3B P49841 1/20 0.44
LTA4H P09960 1/20 0.44
EPHX2 P34913 1/20 0.44
GAA P10253 1/20 0.43
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
ANO1 Q5XXA6 1/20 0.42
CSF1R P07333 1/20 0.42
MET P08581 1/20 0.42
PDGFRB P09619 1/20 0.42
PDGFRA P16234 1/20 0.42
KDR P35968 1/20 0.42
FLT3 P36888 1/20 0.42
ROCK2 O75116 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8987961 0.83 MAPK10 (0.45) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987856 0.83 SMN1; SMN2 (0.45) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987866 0.83 ALDH1A1 (0.46) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987841 0.83 MAPK14 (0.50) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987749 0.83 LTA4H (0.46) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987613 0.82 ANO1 (0.47) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987800 0.81 LTA4H (0.46) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987795 0.81 MAPK10 (0.47) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987803 0.80 CDK2 (0.44) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1
SCHEMBL8987760 0.80 LTA4H (0.44) MAPK14ALDH1A1MAPK10SMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5556859-A N-(4-pyrimidinyl)amide pesticides DOWELANCO (US) 1996-09-17 US disclosed