Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 3/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 9/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987762 | 0.90 | OPRM1 (0.43) | MAPK10MAPK8MAPK9ROCK2CACNA1H | |
| SCHEMBL8988057 | 0.87 | MAPK10 (0.48) | MAPK10MAPK8MAPK9ROCK2CACNA1H | |
| SCHEMBL8987764 | 0.87 | RIOK2 (0.51) | MAPK10MAPK8CACNA1HALDH1A1SMN1; SMN2 | |
| SCHEMBL8987834 | 0.86 | KMT2A (0.51) | MAPK10MAPK8MAPK9RORCALDH1A1 | |
| SCHEMBL8987866 | 0.86 | ALDH1A1 (0.46) | MAPK10ROCK2ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8987813 | 0.85 | ALDH1A1 (0.49) | MAPK10MAPK8ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8987826 | 0.84 | CACNA1H (0.48) | MAPK10MAPK8MAPK9ROCK2CACNA1H | |
| SCHEMBL8987842 | 0.83 | SMN1; SMN2 (0.56) | MAPK10CACNA1HALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8988013 | 0.83 | RIOK2 (0.48) | MAPK10MAPK8CACNA1HRORCALDH1A1 | |
| SCHEMBL8988041 | 0.82 | POLB (0.57) | MAPK10ALDH1A1SMN1; SMN2L3MBTL1RIOK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |