Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 6/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.47 |
| ▸ | GSK3A | P49840 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.47 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.46 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8987834 | 0.90 | KMT2A (0.51) | RIOK2MAPK10GSK3AKMT2AALDH1A1 | |
| SCHEMBL8987866 | 0.90 | ALDH1A1 (0.46) | RIOK2MAPK10KMT2AALDH1A1MEN1 | |
| SCHEMBL8987813 | 0.89 | ALDH1A1 (0.49) | RIOK2MAPK10GSK3AKMT2AALDH1A1 | |
| SCHEMBL8987819 | 0.87 | MAPK10 (0.45) | RIOK2MAPK10KMT2AALDH1A1MEN1 | |
| SCHEMBL8988013 | 0.87 | RIOK2 (0.48) | RIOK2MAPK10ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL8988041 | 0.86 | POLB (0.57) | RIOK2MAPK10KMT2AALDH1A1MEN1 | |
| SCHEMBL8987842 | 0.85 | SMN1; SMN2 (0.56) | RIOK2MAPK10GSK3AALDH1A1RAB9A | |
| SCHEMBL8988025 | 0.84 | RIOK2 (0.45) | RIOK2MAPK10GSK3AKMT2AALDH1A1 | |
| SCHEMBL8987884 | 0.83 | RIOK2 (0.72) | RIOK2MAPK10GSK3AKMT2AMEN1 | |
| SCHEMBL8987820 | 0.82 | RAB9A (0.49) | RIOK2MAPK10GSK3AKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556859-A | N-(4-pyrimidinyl)amide pesticides | DOWELANCO (US) | 1996-09-17 | — | — | US | disclosed |