Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10844389 | 0.87 | PABPC1 (0.58) | TERTKMT2ANPC1GAASMN1; SMN2 | |
| SCHEMBL1001154 | 0.85 | TERT (0.55) | TERTKMT2AGAASMN1; SMN2HTT | |
| SCHEMBL10968004 | 0.83 | TERT (0.46) | TERTKMT2ANPC1SMN1; SMN2HTT | |
| Paraquat SCHEMBL4086035 | 0.81 | TERT (0.59) | TERTKMT2AGAASMN1; SMN2HTT | |
| SCHEMBL1982598 | 0.81 | TERT (0.49) | TERTKMT2AGAASMN1; SMN2HTT | |
| Hydrochloric Acid SCHEMBL9308918 | 0.78 | GAA (0.59) | KMT2AGAASMN1; SMN2LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL27504916 | 0.78 | GAA (0.59) | KMT2AGAASMN1; SMN2LMNAALDH1A1 | |
| Pyridine SCHEMBL31357297 | 0.78 | GAA (0.45) | KMT2ANPC1GAASMN1; SMN2HTT | |
| Alcohol SCHEMBL27993658 | 0.77 | TERT (0.49) | TERTKMT2AGAASMN1; SMN2HTT | |
| SCHEMBL31397607 | 0.76 | TERT (0.48) | TERTKMT2AGAASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5541000-A | Latent, thermal cure accelerators for epoxy-aromatic amine resins having lowered peak exotherms | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-30 | — | — | US | disclosed |
| EP-0719293-A1 | LATENT, THERMAL CURE ACCELERATORS FOR EPOXY-AROMATIC AMINE RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-07-03 | — | — | EP | disclosed |
| WO-1995005411-A2 | LATENT, THERMAL CURE ACCELERATORS FOR EPOXY-AROMATIC AMINE RESINS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-23 | — | — | WO | disclosed |