SCHEMBL8988302

SCHEMBL8988302

O=C1c2cccc(S(=O)(=O)Cl)c2C(=O)c2cccc(S(=O)(=O)Cl)c21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.53
ALDH1A1 P00352 8/20 0.52
SMN1; SMN2 Q16637 5/20 0.52
MAOA P21397 7/20 0.46
ADORA2A P29274 2/20 0.42
MAPT P10636 7/20 0.40
MAPK1 P28482 6/20 0.40
TDP1 Q9NUW8 4/20 0.40
LMNA P02545 4/20 0.40
HSD17B10 Q99714 3/20 0.40
HPGD P15428 2/20 0.40
ALOX15 P16050 2/20 0.40
MAOB P27338 2/20 0.40
HTT P42858 2/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 5/20 0.38
EGFR P00533 3/20 0.38
RAB9A P51151 2/20 0.38
PABPC1 P11940 1/20 0.38
NSD2 O96028 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1823917 0.94 ALDH1A1 (0.61) STAT3ALDH1A1SMN1; SMN2MAOAADORA2A
SCHEMBL10939238 0.93 ALDH1A1 (0.50) STAT3ALDH1A1SMN1; SMN2MAOAADORA2A
SCHEMBL7253446 0.90 ALDH1A1 (0.51) STAT3ALDH1A1SMN1; SMN2MAOAADORA2A
SCHEMBL11856834 0.83 SMN1; SMN2 (0.46) STAT3ALDH1A1SMN1; SMN2MAOAADORA2A
SCHEMBL2747236 0.81 ALDH1A1 (0.52) STAT3ALDH1A1SMN1; SMN2MAOAMAPT
SCHEMBL28165543 0.80 ALDH1A1 (0.39) STAT3ALDH1A1SMN1; SMN2MAOAADORA2A
SCHEMBL17894508 0.79 TDP1 (0.43) STAT3ALDH1A1SMN1; SMN2MAOAMAPT
SCHEMBL31231406 0.79 STAT3 (0.37) STAT3ALDH1A1SMN1; SMN2MAOAMAPT
SCHEMBL28427875 0.79 STAT3 (0.37) STAT3ALDH1A1SMN1; SMN2MAOAMAPT
SCHEMBL28407982 0.78 STAT3 (0.35) STAT3ALDH1A1SMN1; SMN2MAOAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4505793-A INITIATOR IS BLEND OF 3-KETO-SUBSTITUTED CUMARIN AND HALOGEN COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US claimed
CN-116333511-B Synthesis method of anthraquinone dye 江西扬帆新材料有限公司 2023-12-12 CN disclosed
CN-116333511-A Synthesis method of anthraquinone dye 江西扬帆新材料有限公司 2023-06-27 CN disclosed
EP-0442638-B1 Polymeric compounds DU PONT UK (GB) 1996-07-10 EP disclosed
US-5278022-A Photopolymerizable E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-01-11 US disclosed
EP-0358400-B1 Improvements in or relating to polymeric compounds DU PONT (US) 1993-11-10 EP disclosed
US-5162431-A Photosensitive Binders DU PONT-HOWSON LIMITED (GB) 1992-11-10 US disclosed
US-5120799-A POLYMERIC COMPOUNDS HAVING PENDANT SULPHONATO GROUPS AND METHOD OF PRODUCING THE POLYMERIC COMPOUNDS E. I. DU PONT DE NEMOURS AND COMPANY (INC.) (US) 1992-06-09 US disclosed
EP-0442638-A2 Polymeric compounds Du Pont (UK) Limited (GB) 1991-08-21 EP disclosed
EP-0358400-A2 Improvements in or relating to polymeric compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-03-14 EP disclosed
US-4505793-A INITIATOR IS BLEND OF 3-KETO-SUBSTITUTED CUMARIN AND HALOGEN COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US disclosed