SCHEMBL7253446

SCHEMBL7253446

O=C1c2ccccc2-c2cccc(S(=O)(=O)Cl)c21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
MAPT P10636 7/20 0.47
LMNA P02545 4/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAOA P21397 3/20 0.46
MAPK1 P28482 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
S100A4 P26447 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CES2 O00748 1/20 0.46
APAF1 O14727 1/20 0.46
TERT O14746 1/20 0.46
PLIN1 O60240 1/20 0.46
TDP2 O95551 1/20 0.46
S1PR4 O95977 1/20 0.46
PLA2G1B P04054 1/20 0.46
BCHE P06276 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1823917 0.92 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL8988302 0.90 STAT3 (0.53) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL28165543 0.88 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL10939238 0.83 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL11856834 0.78 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL11294162 0.77 MAOA (0.55) ALDH1A1SMN1; SMN2MAPTMEN1KMT2A
SCHEMBL2747236 0.76 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL9763220 0.76 MAPT (0.52) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL7127239 0.75 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2MAPTLMNAMEN1
SCHEMBL1346951 0.75 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6635399-B2 Self-contained; developer and photosensitive microcapsules encapsulating a photosensitive composition and a color precursor; protective coating on the imaging layer EASTMAN KODAK COMPANY 2003-10-21 US disclosed
US-20020045121-A1 One base photosensitive imaging system EASTMAN KODAL COMPANY 2002-04-18 US disclosed
US-5055372-A Photohardenable composition containing borate salts and ketone initiators THE MEAD CORPORATION (US) 1991-10-08 US disclosed
US-4842981-A RADIATING A COLORLESS, CHROMOGENIC COATING AND A RUPTURABLE CAPSULE CONTAINING PHOTOSENSITIVE MATERIAL; IN PRESENCE OF DEVELOPER THE MEAD CORPORATION (US) 1989-06-27 US disclosed
US-4416966-A Capsular imaging system comprising decolorizing agent THE MEAD CORPORATION (US) 1983-11-22 US disclosed
US-4399209-A Transfer imaging system THE MEAD CORPORATION (US) 1983-08-16 US disclosed