SCHEMBL1823917

SCHEMBL1823917

O=C1c2ccccc2C(=O)c2c1cccc2S(=O)(=O)Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
ADORA2A P29274 2/20 0.52
STAT3 P40763 1/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
CDC25B P30305 1/20 0.48
L3MBTL1 Q9Y468 6/20 0.47
MAPT P10636 5/20 0.47
MAPK1 P28482 5/20 0.47
EGFR P00533 3/20 0.47
TDP1 Q9NUW8 2/20 0.47
LMNA P02545 2/20 0.47
RAB9A P51151 2/20 0.47
PABPC1 P11940 1/20 0.47
NSD2 O96028 1/20 0.47
THRB P10828 1/20 0.44
MAOA P21397 6/20 0.44
ALOX12 P18054 2/20 0.44
CYP3A4 P08684 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8988302 0.94 STAT3 (0.53) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL7253446 0.92 ALDH1A1 (0.51) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL10939238 0.92 ALDH1A1 (0.50) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL11856834 0.85 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL1346951 0.83 ALDH1A1 (0.65) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL11539062 0.82 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL1477522 0.80 STAT3 (0.73) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL230644 0.80 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL29470867 0.80 ALDH1A1 (0.61) ALDH1A1SMN1; SMN2ADORA2ASTAT3MEN1
SCHEMBL6055411 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2ADORA2AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112480402-B Modified polyaniline material, preparation method and application thereof 中山市华洋塑胶颜料有限公司 2024-05-28 CN claimed
CN-112480402-A Modified polyaniline material, preparation method and application thereof 黄寅福 2021-03-12 CN claimed
CN-106824288-A Magnetic quinone amboceptor nano-functional material and its preparation method and application 天津城建大学 2017-06-13 CN claimed
CN-104003518-B A kind of quinonyl terylene net functional material and application thereof 河北科技大学 2016-09-14 CN claimed
EP-0569551-A4 COLLAGEN-BASED ADHESIVES AND SEALANTS AND METHODS OF PREPARATION THEREOF. AUTOGENESIS TECH INC (US) 1995-06-14 EP claimed
EP-0569551-A1 COLLAGEN-BASED ADHESIVES AND SEALANTS AND METHODS OF PREPARATION THEREOF C.R. BARD, INC. (US) 1993-11-18 EP claimed
WO-1992013025-A1 COLLAGEN-BASED ADHESIVES AND SEALANTS AND METHODS OF PREPARATION THEREOF AUTOGENESIS TECHNOLOGIES, INC. (US) 1992-08-06 WO claimed
US-4636459-A PHOTOINITIATOR AND UNSATURATED MONOMER; PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 1987-01-13 US claimed
US-4555474-A IMPROVED PHOTOSENSITIVITY USING HETEROCYCLIC KETONE PHOTOINITIATORS; LITHOGRAPHY; PHOTORESISTS FUJI PHOTO FILM CO., LTD. (JP) 1985-11-26 US claimed
US-4505793-A INITIATOR IS BLEND OF 3-KETO-SUBSTITUTED CUMARIN AND HALOGEN COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1985-03-19 US claimed
CN-118518868-A Immunosensor of vitamin B2, preparation method and application 中芯维康医疗科技(重庆)有限责任公司 2024-08-20 CN disclosed
CN-112480402-B Modified polyaniline material, preparation method and application thereof 中山市华洋塑胶颜料有限公司 2024-05-28 CN disclosed
EP-4337258-A1 DERIVATIZED OR RAPIDLY POLYMERIZING COLLAGEN COMPOSITIONS FOR TISSUE AUGMENTATION CONTAINING NON-RESORBABLE OR SLOWLY RESORBABLE POLYMERS Shanghai Qisheng Biological Preparation Co., Ltd. (CN) 2024-03-20 EP disclosed
CN-117342990-A Sulfonamide compound, preparation method and application thereof, pesticide preparation and medicament 贵州大学 2024-01-05 CN disclosed
CN-117342989-A Anthracene-9, 10-diketone compound, preparation method and application thereof, application of sulfonamide compound and medicament 山东农业大学 2024-01-05 CN disclosed
EP-0005474-A2 Anthraquinone compounds, process for preparing them and their use for dyeing and printing synthetic materials BAYER AG (DE) 1979-11-28 EP disclosed
EP-0005379-A2 Photosensitive compositions containing carbonylic halides as activators Dynachem Corporation (US) 1979-11-14 EP disclosed
EP-0005380-A2 Phototropic photosensitive compositions containing a fluoran colorformer Dynachem Corporation (US) 1979-11-14 EP disclosed
US-4065446-A Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical BAYER AKTIENGESELLSCHAFT (DT) 1977-12-27 US disclosed
US-4060549-A Process for preparing sulfonic acid fluorides BAYER AKTIENGESELLSCHAFT (DT) 1977-11-29 US disclosed