Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988701 | 0.95 | HRH3 (0.38) | HRH3HDAC1CTSDMCHR1PTPN1 | |
| Hydrochloric Acid SCHEMBL8988625 | 0.92 | OPRD1 (0.36) | HRH3OPRD1MCHR1 | |
| Hydrochloric Acid SCHEMBL8988652 | 0.86 | HRH3 (0.33) | HRH3 | |
| SCHEMBL7395923 | 0.82 | HRH3 (0.41) | HRH3OPRD1KDM4C | |
| Hydrochloric Acid SCHEMBL7274423 | 0.82 | HRH3 (0.40) | HRH3OPRD1KDM4C | |
| SCHEMBL8988799 | 0.81 | HRH3 (0.40) | HRH3HDAC1CTSDPTPN1 | |
| Hydrochloric Acid SCHEMBL8988618 | 0.80 | HRH3 (0.39) | HRH3HDAC1CTSDPTPN1 | |
| SCHEMBL8988630 | 0.78 | PTPN1 (0.40) | HRH3HDAC1CTSDPTPN1 | |
| SCHEMBL7384118 | 0.77 | HRH3 (0.40) | HRH3OPRD1HDAC1CTSD | |
| Hydrochloric Acid SCHEMBL7281181 | 0.76 | HRH3 (0.39) | HRH3OPRD1HDAC1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |