Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | GCK | P35557 | 2/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8988899 | 0.95 | HRH3 (0.38) | HRH3HDAC1CTSDPTPN1MCHR1 | |
| Hydrochloric Acid SCHEMBL8988652 | 0.91 | HRH3 (0.33) | HRH3F10GCKEP300 | |
| Hydrochloric Acid SCHEMBL8988625 | 0.86 | OPRD1 (0.36) | HRH3MCHR1 | |
| SCHEMBL8988799 | 0.82 | HRH3 (0.40) | HRH3HDAC1CTSDPTPN1KDM4E | |
| SCHEMBL7384118 | 0.82 | HRH3 (0.40) | HRH3HDAC1CTSDF10ACHE | |
| Hydrochloric Acid SCHEMBL8988618 | 0.81 | HRH3 (0.39) | HRH3HDAC1CTSDPTPN1KDM4E | |
| Hydrochloric Acid SCHEMBL7281181 | 0.81 | HRH3 (0.39) | HRH3HDAC1CTSDF10ACHE | |
| SCHEMBL8988630 | 0.79 | PTPN1 (0.40) | HRH3HDAC1CTSDPTPN1 | |
| SCHEMBL8988853 | 0.77 | HRH3 (0.37) | HRH3HDAC1CTSDPTPN1F10 | |
| SCHEMBL8988689 | 0.77 | ITGB3 (0.43) | HRH3HDAC1PTPN1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489693-A | ANTICOAGULANTS | DR. KARK THOMAE, GMBH (DE) | 1996-02-06 | — | — | US | disclosed |
| EP-0567968-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |