Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989164 | 0.92 | BCHE (0.34) | CCR6PAX8L3MBTL1MBOAT4HDAC3 | |
| SCHEMBL8988912 | 0.85 | TSHR (0.32) | TSHRCCR6PAX8MBOAT4CTSB | |
| SCHEMBL8989010 | 0.80 | HTT (0.53) | HTT | |
| SCHEMBL8989003 | 0.80 | HTT (0.53) | HTT | |
| SCHEMBL8989027 | 0.78 | HSD17B10 (0.33) | L3MBTL1MBOAT4CTSB | |
| SCHEMBL8989019 | 0.77 | TSHR (0.36) | TSHRCCR6PAX8L3MBTL1CTSB | |
| SCHEMBL8622951 | 0.76 | ALOX5 (0.48) | CCR6PAX8L3MBTL1HTTHDAC3 | |
| SCHEMBL8618140 | 0.76 | KMT2A (0.39) | CCR6PAX8HDAC3HDAC1HDAC2 | |
| SCHEMBL9879981 | 0.75 | MAPT (0.49) | CCR6PAX8L3MBTL1HTTHDAC3 | |
| SCHEMBL6618522 | 0.75 | MAPT (0.49) | CCR6PAX8L3MBTL1HTTHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488140-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5294734-A | 1-phosphato-4-amino-pent-2-enoic acids and derivatives | CIBA-GEIGY CORP. (US) | 1994-03-15 | — | — | US | disclosed |