Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | CASP1 | P29466 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | CASP7 | P55210 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545080 | 0.80 | ALDH1A1 (0.54) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL625453 | 0.78 | ALDH1A1 (0.47) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL20570695 | 0.78 | MET (0.48) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL28109319 | 0.78 | ALDH1A1 (0.39) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL6978780 | 0.74 | ALDH1A1 (0.41) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL26259566 | 0.73 | POLB (0.48) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL17821196 | 0.73 | ALDH1A1 (0.55) | ALDH1A1POLBKDM4EMEN1KMT2A | |
| SCHEMBL15231432 | 0.73 | KDM4E (0.49) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL23954258 | 0.72 | GLO1 (0.51) | GLO1ALDH1A1POLBKDM4EMEN1 | |
| SCHEMBL857504 | 0.72 | CDK2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489685-A | CATALYTIC REACTION OF TRIMETHYLSILYLACETYLENE WITH HALOGENATED HYDROXY PYRIDINE ESTER, THEN INCUBATION WITH ACID AND TREATMENT WITH STRONG BASE OR HALIDE FOR CYCLIZATION | MERCK & CO., LTD. (US) | 1996-02-06 | — | — | US | disclosed |