SCHEMBL898940

SCHEMBL898940

OC[C@@H]1CCCC[C@]1(O)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 9/20 0.49
SLC6A4 P31645 9/20 0.49
OPRM1 P35372 7/20 0.49
OPRD1 P41143 3/20 0.49
OPRK1 P41145 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
SLC22A1 O15245 3/20 0.46
CHRM2 P08172 1/20 0.46
CHRM1 P11229 1/20 0.46
NPY1R P25929 1/20 0.43
HTT P42858 1/20 0.43
NPY2R P49146 1/20 0.43
PTGS2 P35354 1/20 0.42
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CNR2 P34972 2/20 0.40
CNR1 P21554 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL898941 1.00 SLC6A2 (0.49) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL4989694 0.85 SLC6A2 (0.51) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL7595748 0.82 OPRM1 (0.47) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL21483713 0.81 SLC6A2 (0.42) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL28739214 0.81 SLC22A1 (0.68) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL150032 0.81 SLC6A4 (0.73) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL28002157 0.80 SLC6A4 (0.47) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL3995682 0.79 OPRM1 (0.43) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL3822905 0.79 OPRM1 (0.43) SLC6A2SLC6A4OPRM1OPRD1OPRK1
SCHEMBL3822529 0.79 OPRM1 (0.43) SLC6A2SLC6A4OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US claimed
EP-2726530-B1 HYBRID EPOXY RESIN ADDUCTS BLUE CUBE IP LLC (US) 2018-09-12 EP disclosed
EP-2621992-B1 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF BLUE CUBE IP LLC (US) 2017-07-26 EP disclosed
US-9371414-B2 Epoxy resin adducts and thermosets thereof BLUE CUBE IP LLC (US) 2016-06-21 US disclosed
CN-103140531-B Prepare the method for epoxy resin Blue Cube Intellectual Property Co.,Ltd. (US) 2016-05-04 CN disclosed
EP-2621995-B1 ADVANCED EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2016-03-23 EP disclosed
US-9284434-B2 Epoxy resin compositions BLUE CUBE IP LLC (US) 2016-03-15 US disclosed
EP-2621990-B1 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM BLUE CUBE IP LLC (US) 2016-02-24 EP disclosed
US-9255177-B2 Hybrid epoxy resin adducts BLUE CUBE IP LLC (US) 2016-02-09 US disclosed
WO-2015148039-A1 PARTIALLY HYDROLYZED EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2015-10-01 WO disclosed
WO-2013006250-A1 HYBRID EPOXY RESIN ADDUCTS DOW GLOBAL TECHNOLOGIES LLC (US) 2013-01-10 WO disclosed
WO-2012050777-A1 ADVANCED POLY EPOXY ESTER RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-19 WO disclosed
WO-2012050688-A2 EPOXY RESIN ADDUCTS AND THERMOSETS THEREOF DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-19 WO disclosed
WO-2012047420-A2 THERMOSETTABLE COMPOSITIONS AND THERMOSETS THEREFROM DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-12 WO disclosed
WO-2012044458-A1 ADVANCED EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
WO-2012044455-A1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
WO-2012044442-A1 PROCESS FOR PREPARING EPOXY RESINS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
WO-2012044443-A1 EPOXY RESIN COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
WO-2012044490-A1 COATING COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-04-05 WO disclosed
US-4125558-A Method for the manufacture of the cis-2-hydroxy-2-phenyl-r-1-cyclohexanecarboxylic acid GUIDOTTI INTERNATIONALE S.A. (IT) 1978-11-14 US disclosed