SCHEMBL8989665

SCHEMBL8989665

Nc1c(O)cccc1NC=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
KDM5A P29375 2/20 0.41
TSHR P16473 2/20 0.38
PABPC1 P11940 1/20 0.37
ERN1 O75460 1/20 0.36
EGFR P00533 2/20 0.36
ALDH1A1 P00352 2/20 0.35
TRIM24 O15164 1/20 0.34
TRIM33 Q9UPN9 1/20 0.34
GAA P10253 3/20 0.34
HTT P42858 2/20 0.34
TDP1 Q9NUW8 3/20 0.33
KDM4E B2RXH2 2/20 0.33
ALOX15 P16050 2/20 0.33
MAPT P10636 1/20 0.33
KMT2A Q03164 1/20 0.33
HIF1A Q16665 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27578629 0.79 TSHR (0.40) CASP7KDM5ATSHRPABPC1ALDH1A1
SCHEMBL3567350 0.79 ERN1 (0.48) KDM5ATSHRPABPC1ERN1EGFR
SCHEMBL29876843 0.79 GAA (0.50) KDM5ATSHRPABPC1EGFRALDH1A1
SCHEMBL1939410 0.79 GAA (0.50) KDM5ATSHRPABPC1EGFRALDH1A1
SCHEMBL11207914 0.76 TSHR (0.44) KDM5ATSHRPABPC1ERN1EGFR
SCHEMBL564616 0.76 EGFR (0.47) G6PDCASP7CASP6TSHREGFR
SCHEMBL28031204 0.76 ESR2 (0.47) KDM5ATSHRPABPC1ERN1ALDH1A1
SCHEMBL534334 0.76 G6PD (0.52) G6PDCASP7CASP6KDM5ATSHR
SCHEMBL29188888 0.74 G6PD (0.43) G6PDCASP7CASP6TSHREGFR
SCHEMBL9702646 0.73 KDM5A (0.39) KDM5ATSHRPABPC1ERN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5536876-A Formylamino-aminophenol compounds and their use in preparation of fiber-reactive formazan dyes BASF AKTIENGESELLSCHAFT (DE) 1996-07-16 US disclosed