Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551394 | 0.77 | ALDH1A1 (0.47) | TSHRERN1ALDH1A1GAATRIM24 | |
| SCHEMBL3567350 | 0.76 | ERN1 (0.48) | KDM5ATSHRPABPC1ERN1ALDH1A1 | |
| SCHEMBL29876843 | 0.76 | GAA (0.50) | KDM5ATSHRPABPC1ALDH1A1GAA | |
| SCHEMBL1939410 | 0.76 | GAA (0.50) | KDM5ATSHRPABPC1ALDH1A1GAA | |
| SCHEMBL11207914 | 0.73 | TSHR (0.44) | KDM5ATSHRPABPC1ERN1ALDH1A1 | |
| SCHEMBL28031204 | 0.73 | ESR2 (0.47) | KDM5ATSHRPABPC1ERN1ALDH1A1 | |
| SCHEMBL8989665 | 0.73 | G6PD (0.42) | KDM5ATSHRPABPC1ERN1ALDH1A1 | |
| SCHEMBL13596863 | 0.73 | TDP1 (0.40) | TSHRERN1ALDH1A1GAAMAPT | |
| SCHEMBL7088879 | 0.69 | ALDH1A1 (0.54) | TSHRALDH1A1KDM4ELMNACA12 | |
| SCHEMBL3562175 | 0.69 | ERN1 (0.43) | KDM5ATSHRPABPC1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130472-A | TOTAL SYNTHESIS OF ERBSTATIN ANALOGS | FARMITALIA CARLO ERBA S.R.L. (IT) | 1992-07-14 | — | — | US | disclosed |