Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4726672 | 0.82 | TDP1 (0.46) | TDP1LMNAKMT2A | |
| SCHEMBL8989691 | 0.81 | TDP1 (0.42) | TDP1ALDH1A1HPGDLMNATSHR | |
| SCHEMBL4528744 | 0.80 | HPGD (0.45) | TDP1ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL25181226 | 0.79 | TDP1 (0.40) | TDP1ALDH1A1HPGDLMNAKMT2A | |
| SCHEMBL15803300 | 0.78 | TDP1 (0.39) | TDP1ALDH1A1HPGDLMNA | |
| SCHEMBL1181113 | 0.77 | TAAR1 (0.41) | — | |
| SCHEMBL7846668 | 0.76 | CAMK2A (0.41) | — | |
| SCHEMBL6247927 | 0.72 | CAMK2A (0.38) | — | |
| SCHEMBL9230251 | 0.72 | GPR84 (0.40) | — | |
| SCHEMBL6883197 | 0.72 | CA12 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0600370-B1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| EP-0600370-A1 | Di-(3-(2-chloroethylsulphonyl)-1-propylamine hydrochloride and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-08 | — | — | EP | disclosed |