Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063307 | 0.78 | TDP1 (0.40) | TDP1TSHRCA1CA2CA7 | |
| SCHEMBL7772546 | 0.77 | — | — | |
| SCHEMBL12723411 | 0.76 | — | — | |
| SCHEMBL5873282 | 0.74 | TDP1 (0.61) | TDP1TSHRMEN1KMT2ACA1 | |
| SCHEMBL6856668 | 0.74 | TDP1 (0.43) | TDP1TSHRMEN1POLBKMT2A | |
| SCHEMBL1471358 | 0.73 | TDP1 (0.51) | TDP1TSHRMEN1POLBKMT2A | |
| SCHEMBL8063306 | 0.72 | TDP1 (0.59) | TDP1TSHRMEN1KMT2ACA1 | |
| SCHEMBL933075 | 0.72 | TDP1 (0.42) | TDP1TSHRMEN1POLBKMT2A | |
| SCHEMBL555029 | 0.72 | — | — | |
| SCHEMBL10225098 | 0.71 | TDP1 (0.37) | TDP1TSHRMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504107-A | ANTICOAGULANTS, PREVENTING ATHEROSCLEROSIS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1996-04-02 | — | — | US | disclosed |