Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8063306 | 0.98 | TDP1 (0.59) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL3430807 | 0.93 | TDP1 (0.63) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL11490547 | 0.85 | TDP1 (0.56) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL8775561 | 0.85 | TDP1 (0.47) | TDP1TSHRCYP3A4PKMSMN1; SMN2 | |
| SCHEMBL1471358 | 0.85 | TDP1 (0.51) | TDP1TSHRNPSR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11829533 | 0.85 | TDP1 (0.56) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL8670951 | 0.85 | TDP1 (0.61) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL11357983 | 0.83 | TDP1 (0.59) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL4558499 | 0.83 | TDP1 (0.64) | TDP1TSHRCYP3A4NPSR1PKM | |
| SCHEMBL19296598 | 0.81 | TDP1 (0.67) | TDP1TSHRCYP3A4NPSR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190023692-A1 | QUINOXALINONES AND DIHYDROQUINOXALINONES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | JANSSEN SCIENCES IRELAND UC (IE) | 2019-01-24 | — | — | US | disclosed |
| US-10081618-B2 | Quinoxalinones and dihydroquinoxalinones as respiratory syncytial virus ativiral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-09-25 | — | — | US | disclosed |
| EP-3131905-B1 | SPIRO UREA COMPOUNDS AS RSV ANTIVIRAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-28 | — | — | EP | disclosed |
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |
| US-9845321-B2 | 1,3-dihydro-2H-benzimidazol-2-one derivatives substituted with heterocycles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2017-12-19 | — | — | US | disclosed |
| US-20170260166-A1 | QUINOXALINONES AND DIHYDROQUINOXALINONES AS RESPIRATORY SYNCYTIAL VIRUS ATIVIRAL AGENTS | JANSSEN INFECTIOUS DISEASES BVBA (BE) | 2017-09-14 | — | — | US | disclosed |
| US-9738652-B2 | Spiro urea compounds as RSV antiviral compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2017-08-22 | — | — | US | disclosed |
| EP-2909195-B1 | RSV ANTIVIRAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-06-14 | — | — | EP | disclosed |
| US-9617289-B2 | RSV antiviral compounds | JANSSEN SCIENCES IRELAND UC (IE) | 2017-04-11 | — | — | US | disclosed |
| EP-3131905-A1 | SPIRO UREA COMPOUNDS AS RSV ANTIVIRAL COMPOUNDS | Janssen Sciences Ireland UC (IE) | 2017-02-22 | — | — | EP | disclosed |
| US-20060079711-A1 | Method of producing diol derivatives | HAYASHI TOSHIO | 2006-04-13 | — | — | US | disclosed |
| US-7005536-B2 | Method for producing diol derivatives | NIPPON SHOKUBAI CO., LTD. (JP) | 2006-02-28 | — | — | US | disclosed |
| EP-1553076-A1 | PROCESS FOR PRODUCING DIOL DERIVATIVE | Nippon Shokubai Co., Ltd. (JP) | 2005-07-13 | — | — | EP | disclosed |
| US-20040138409-A1 | Method for producing diol derivatives | NIPPON SHOKUBAI CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
| EP-0082188-B1 | FLEXIBLE FILM LAMINATES AND RETORTABLE FOOD POUCHES FABRICATED THEREFROM | MOBIL OIL CORPORATION (US) | 1987-04-08 | — | — | EP | disclosed |
| EP-0082188-A4 | FLEXIBLE FILM LAMINATES AND RETORTABLE FOOD POUCHES FABRICATED THEREFROM. | MOBIL OIL CORP (US) | 1983-10-06 | — | — | EP | disclosed |
| EP-0082188-A1 | FLEXIBLE FILM LAMINATES AND RETORTABLE FOOD POUCHES FABRICATED THEREFROM. | MOBIL OIL CORP (US) | 1983-06-29 | — | — | EP | disclosed |
| WO-1982004429-A1 | FLEXIBLE FILM LAMINATES AND RETORTABLE FOOD POUCHES FABRICATED THEREFROM | MOBIL OIL CORP (US) | 1982-12-23 | — | — | WO | disclosed |
| US-4360551-A | Flexible film laminate especially adapted for use in the construction of a retortable food pouch | MOBIL OIL CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4126647-A | ETHYLENE POLYMER/ACRYLONITRILE POLYMER COMPOSITES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-11-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190023692-A1 | QUINOXALINONES AND DIHYDROQUINOXALINONES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS | SQOR, SDHA, DHX15 | TDP1 2567/4885TSHR 4855/4885CYP3A4 341/4885 |
| US-20170260166-A1 | QUINOXALINONES AND DIHYDROQUINOXALINONES AS RESPIRATORY SYNCYTIAL VIRUS ATIVIRAL AGENTS | ATIC, DHX15, SQOR | TDP1 2921/4885TSHR 4847/4885CYP3A4 364/4885 |
| US-10081618-B2 | Quinoxalinones and dihydroquinoxalinones as respiratory syncytial virus ativiral agents | ATIC, DHX15, SQOR | TDP1 2921/4885TSHR 4847/4885CYP3A4 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.