SCHEMBL8063306

SCHEMBL8063306

C=CCOCC(=O)OCC=C.[NaH]

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.59
TSHR P16473 6/20 0.46
CYP3A4 P08684 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
PKM P14618 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAPT P10636 1/20 0.37
CACNA1B Q00975 1/20 0.37
APBA1 Q02410 1/20 0.37
ALDH1A1 P00352 8/20 0.36
HSD17B10 Q99714 6/20 0.36
KDM4E B2RXH2 4/20 0.36
HPGD P15428 4/20 0.36
GAA P10253 1/20 0.36
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA7 P43166 1/20 0.33
TP53 P04637 2/20 0.32
HIF1A Q16665 2/20 0.32
EPHX2 P34913 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5873282 0.98 TDP1 (0.61) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL3430807 0.91 TDP1 (0.63) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL11357983 0.85 TDP1 (0.59) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL11490547 0.83 TDP1 (0.56) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL8775561 0.83 TDP1 (0.47) TDP1TSHRCYP3A4PKMSMN1; SMN2
SCHEMBL1471358 0.83 TDP1 (0.51) TDP1TSHRNPSR1SMN1; SMN2ALDH1A1
SCHEMBL11829533 0.83 TDP1 (0.56) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL8670951 0.83 TDP1 (0.61) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL4558499 0.81 TDP1 (0.64) TDP1TSHRCYP3A4NPSR1PKM
SCHEMBL19296598 0.79 TDP1 (0.67) TDP1TSHRCYP3A4NPSR1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114846078-B Inverse latex for cosmetic compositions combining tetrasodium salt of glutamic acid N, N-diacetic acid as chelating agent and polyelectrolyte comprising AMPS and acrylamide 化工产品开发公司SEPPIC 2024-03-29 CN claimed
CN-114845687-B Composition for lightening or whitening keratin materials 莱雅公司 2024-04-16 CN disclosed
CN-113318012-B Composition for topical application in the form of a gel containing mineralized water 化工产品开发公司SEPPIC 2024-03-12 CN disclosed
CN-112955227-B Cosmetic composition in the form of a water-in-oil emulsion for treating hair to improve combing 化工产品开发公司SEPPIC 2023-07-18 CN disclosed
CN-111971315-B Thickened self-invertible inverse latex comprising surfactant species of the polyglycerol ester family as inverse and compositions containing same 化工产品开发公司SEPPIC 2023-01-06 CN disclosed
EP-4027972-A1 ANHYDROUS COMPOSITION FOR TOPICAL USE THAT IS IN THE FORM OF A DISPERSED PHASE BASED ON AT LEAST ONE SHORT DIOL IN A CONTINUOUS FATTY PHASE Société d'Exploitation de Produits pour les Industries Chimiques SEPPIC (FR) 2022-07-20 EP disclosed
CN-113939264-A Composition comprising at least one compound of the N-acylaminoamide family and at least one alkylpolyglycoside 莱雅公司 2022-01-14 CN disclosed
CN-111479835-B Self-reversible inverse latex comprising an alkyl polyglycoside as inverse and use thereof as thickener for detergent or cleaning formulations for industrial or domestic use 化工产品开发公司SEPPIC 2021-11-26 CN disclosed
CN-108601716-B Gel/gel-type composition based on pigments coated with hydrophobic substances and liquid fatty acid and/or diol compounds 莱雅公司 2021-11-16 CN disclosed
WO-2021028633-A1 ANHYDROUS COMPOSITION FOR TOPICAL USE THAT IS IN THE FORM OF A DISPERSED PHASE BASED ON AT LEAST ONE SHORT DIOL IN A CONTINUOUS FATTY PHASE SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) 2021-02-18 WO disclosed
CN-106794135-B Gel-type cosmetic composition with improved retention 欧莱雅 2020-12-22 CN disclosed
CN-111971315-A Thickened self-reversible inverse latex comprising surfactant species of the polyglycerol ester family as inverse agent, and compositions containing same 化工产品开发公司SEPPIC 2020-11-20 CN disclosed
CN-111479835-A Self-reversible inverse latex comprising an alkyl polyglycoside as inverse and use thereof as thickener for detergent or cleaning formulations for industrial or domestic use 化工产品开发公司SEPPIC 2020-07-31 CN disclosed
CN-111356431-A Self-reversible inverse latex comprising an alkyl polyglycoside as inverse, use thereof as thickener, and cosmetic composition comprising same 化工产品开发公司SEPPIC 2020-06-30 CN disclosed
CN-111065439-A Gelling composition comprising a dispersion of solid aggregates 欧莱雅 2020-04-24 CN disclosed
WO-2015105675-A1 CEMENTING FLUID AND METHODS FOR PRODUCING THE SAME HERCULES INCORPORATED (US) 2015-07-16 WO disclosed
US-20150191642-A1 CEMENTING FLUID AND METHODS FOR PRODUCING THE SAME HERCULES INCORPORATED 2015-07-09 US disclosed
EP-1010708-A1 New inverse latex stable against electrolytes, production process and use in cosmetics SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES, S.E.P.P.I.C. (FR) 2000-06-21 EP disclosed