Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990040 | 0.88 | ALDH1A1 (0.43) | ALDH1A1KDM4EMAPTL3MBTL1MEN1 | |
| SCHEMBL11044229 | 0.83 | ALDH1A1 (0.60) | ALDH1A1KDM4EBAZ2BBAZ2AMAPT | |
| SCHEMBL1266941 | 0.82 | ALKBH5 (0.49) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL11042142 | 0.81 | KDM4E (0.58) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL5159217 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL692667 | 0.79 | MAPT (0.52) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL11420507 | 0.79 | ALDH1A1 (0.78) | ALDH1A1KDM4EBAZ2BBAZ2AMAPT | |
| SCHEMBL9384017 | 0.79 | ALDH1A1 (0.82) | ALDH1A1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL9397382 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EMAPTL3MBTL1POLB | |
| SCHEMBL11420534 | 0.77 | ALDH1A1 (0.68) | ALDH1A1KDM4EBAZ2BBAZ2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35359-E | Amine salts of azo pigments based on pyrazolone derivatives | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| US-5151505-A | Monoazo dyes containing hydroxypyrazole groups | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-4992495-A | Yellow pigment | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4980458-A | Mixed sodium, ammonium and/or calcium salt crystals of laked monoazo disulfonated pyrazolone pigments | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0263074-A2 | Mixed crystals of laked azo dyes | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |