SCHEMBL8990089

SCHEMBL8990089

CC1=NN(c2cc(Cl)c(S(=O)(=O)O)cc2Cl)CC1=O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
MAPT P10636 2/20 0.39
CASP6 P55212 1/20 0.39
KMT2A Q03164 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11683076 0.76 MYC (0.50) ALDH1A1MAPTCASP6KMT2ALMNA
SCHEMBL11431757 0.76 ALDH1A1 (0.43) ALDH1A1MAPTCASP6KMT2ALMNA
SCHEMBL10412445 0.75 ALDH1A1 (0.36) ALDH1A1MAPTCASP6KMT2AL3MBTL1
SCHEMBL29677237 0.73 MAPT (0.67) ALDH1A1MAPTCASP6KMT2AL3MBTL1
SCHEMBL9770538 0.73 MAPT (0.67) ALDH1A1MAPTCASP6KMT2AL3MBTL1
SCHEMBL11509806 0.72 MAPT (0.41) ALDH1A1MAPTCASP6KMT2ALMNA
SCHEMBL8990101 0.71 ALDH1A1 (0.56) ALDH1A1MAPTCASP6KMT2ALMNA
SCHEMBL4565135 0.68 CA1 (0.39) ALDH1A1CASP6KMT2AL3MBTL1LMNA
SCHEMBL28611890 0.67 ALDH1A1 (0.36) ALDH1A1MAPTCASP6KMT2A
SCHEMBL10360503 0.67 SUMO2 (0.38) KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35359-E Amine salts of azo pigments based on pyrazolone derivatives CIBA-GEIGY CORPORATION (US) 1996-10-22 US disclosed
EP-0241413-B1 AMINE SALTS OF AZO COMPOUNDS CIBA-GEIGY AG (CH) 1993-03-03 EP disclosed
US-5151505-A Monoazo dyes containing hydroxypyrazole groups CIBA-GEIGY CORPORATION (US) 1992-09-29 US disclosed
US-4992495-A Yellow pigment CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
EP-0241413-A2 Amine salts of azo compounds CIBA-GEIGY AG (CH) 1987-10-14 EP disclosed
US-4339525-A ADDITION POLYMERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-07-13 US disclosed
EP-0054515-A1 Reactive dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1982-06-23 EP disclosed
US-4229517-A Dot-etchable photopolymerizable elements E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-10-21 US disclosed
US-4229520-A Photo-polymerization and development process which produces dot-etchable material E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-10-21 US disclosed
US-4173673-A Dot-etchable masks from photopolymerizable elements E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-11-06 US disclosed