Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | CASP6 | P55212 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29677237 | 1.00 | MAPT (0.67) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL18267342 | 0.80 | MAPT (0.81) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL9770298 | 0.79 | MAPT (0.48) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL11501543 | 0.76 | MAPT (0.59) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL8072508 | 0.76 | MAPT (0.74) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL8990089 | 0.73 | ALDH1A1 (0.39) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL9770328 | 0.73 | MAPT (0.66) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL10594920 | 0.70 | MAPT (0.57) | MAPTKMT2AALDH1A1CASP6GAA | |
| SCHEMBL28611890 | 0.69 | ALDH1A1 (0.36) | MAPTKMT2AALDH1A1CASP6 | |
| SCHEMBL29851934 | 0.69 | MAPT (0.60) | MAPTKMT2AALDH1A1CASP6GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5001220-A | Pyrazolone substituted copolyarylene sulfide | BAYER AG (DE) | 1991-03-19 | — | — | US | disclosed |
| EP-0219232-B1 | WATER-SOLUBLE DYE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-29 | — | — | EP | disclosed |
| EP-0332966-A1 | High-molecular, optionally branched-chain co-polyarylene sulphides, their production and their use | BAYER AG (DE) | 1989-09-20 | — | — | EP | disclosed |
| US-4772323-A | IMPROVED STORAGE AND EJECTION STABILITY | CANON KABUSHIKI KAISHA (JP) | 1988-09-20 | — | — | US | disclosed |
| US-4758658-A | Water-soluble formazan dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-19 | — | — | US | disclosed |
| EP-0219232-A2 | Water-soluble dye | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-22 | — | — | EP | disclosed |