SCHEMBL8990126

SCHEMBL8990126

Cc1cc(Cl)cc(S(=O)(=O)O)c1N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
SENP2 Q9HC62 3/20 0.38
SENP1 Q9P0U3 3/20 0.38
SUMO2 P61956 2/20 0.38
SUMO1 P63165 2/20 0.38
SENP7 Q9BQF6 2/20 0.38
SENP3 Q9H4L4 2/20 0.38
CYP1A1 P04798 1/20 0.38
CYP1A2 P05177 1/20 0.38
ENPP2 Q13822 1/20 0.38
KDM4E B2RXH2 3/20 0.36
ALDH1A1 P00352 3/20 0.36
TP53 P04637 2/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
RECQL P46063 2/20 0.36
KMT2A Q03164 2/20 0.36
APP P05067 1/20 0.36
CYP3A4 P08684 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10133622 0.86 CA1 (0.45) CA1CA2KDM4EALDH1A1TP53
SCHEMBL11324456 0.82 L3MBTL1 (0.46) CA1CA2CYP1A1CYP1A2KDM4E
SCHEMBL1957301 0.82 CA1 (0.52) CA1CA2KDM4EALDH1A1RECQL
SCHEMBL4698065 0.80 ALDH1A1 (0.52) CA1CA2SENP2SENP1SUMO2
SCHEMBL29633914 0.80 KDM4E (0.52) CA1CA2SENP2SENP1SUMO2
SCHEMBL10847621 0.80 ALDH1A1 (0.46) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL1364945 0.80 KDM4E (0.52) CA1CA2SENP2SENP1SUMO2
SCHEMBL30922153 0.80 ALDH1A1 (0.46) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL6931230 0.78 ENPP2 (0.41) SENP2SENP1SUMO2SUMO1SENP7
SCHEMBL9660935 0.78 POLB (0.38) CA1CA2HPGDHSD17B10CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE35359-E Amine salts of azo pigments based on pyrazolone derivatives CIBA-GEIGY CORPORATION (US) 1996-10-22 US disclosed
EP-0416363-B1 Modification of Polyarylenesulfides BAYER AG (DE) 1995-11-15 EP disclosed
EP-0333653-B1 Reactive dyes, process for their preparation and their use CIBA GEIGY AG (CH) 1994-06-08 EP disclosed
US-5286809-A Glass fiber reinforced polyamide 6, polyphenylene sulfide grated with sulfonaphthalene diacid anhydride BAYER AG (DE) 1994-02-15 US disclosed
EP-0241413-B1 AMINE SALTS OF AZO COMPOUNDS CIBA-GEIGY AG (CH) 1993-03-03 EP disclosed
US-5151505-A Monoazo dyes containing hydroxypyrazole groups CIBA-GEIGY CORPORATION (US) 1992-09-29 US disclosed
EP-0492246-A2 Thermoplastic moulding compositions BAYER AG (DE) 1992-07-01 EP disclosed
US-5086129-A POLYARYLENE SULPHIDE MODIFIED WITH ARYL SULFONIC ACID CONTAINING AMINO OR HYDROXYL GROUP BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
EP-0416363-A2 Modification of Polyarylenesulfides BAYER AG (DE) 1991-03-13 EP disclosed
US-4992495-A Yellow pigment CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed
US-4767844-A COUPLING DIAZO COMPONENT HAVING SULFONIC ACID GROUP WITH A MIXTURE OF 2-HYDROXY-3-NAPHTHOIC ACID AND THE AMIDE DERIVATIVES THEREOF DAINIPPON INK AND CHEMICALS, INC. (JP) 1988-08-30 US disclosed
US-4754023-A Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member CIBA-GEIGY CORPORATION (US) 1988-06-28 US disclosed
EP-0263074-A2 Mixed crystals of laked azo dyes CIBA-GEIGY AG (CH) 1988-04-06 EP disclosed
EP-0159292-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1988-01-07 EP disclosed
EP-0202906-A1 Process for producing azo lake pigments DAINIPPON INK AND CHEMICALS, INC. (JP) 1986-11-26 EP disclosed
EP-0159292-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-10-23 EP disclosed
EP-0144766-A2 Reactive dyes, their preparation and their use CIBA-GEIGY AG (CH) 1985-06-19 EP disclosed
EP-0073406-B1 WATER-SOLUBLE MONOAZO PYRAZOLONE COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-03-20 EP disclosed
EP-0073406-A1 Water-soluble monoazo pyrazolone compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-03-09 EP disclosed
US-4329282-A Fluoro-triazine-containing fibre-reactive disazo dyestuffs BAYER AKTEINGESELLSCHAFT (DE) 1982-05-11 US disclosed