SCHEMBL8990142

SCHEMBL8990142

CC(C)(C)c1cc(-c2ccccc2)cc(-c2cc(-c3ccccc3)cc(C(C)(C)C)c2O)c1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.59
CA1 P00915 1/20 0.59
CYP1A2 P05177 2/20 0.52
CYP2C9 P11712 2/20 0.52
CYP2C19 P33261 2/20 0.52
PTPN1 P18031 2/20 0.46
MEN1 O00255 1/20 0.45
GAA P10253 1/20 0.45
KMT2A Q03164 1/20 0.45
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
PTPN5 P54829 1/20 0.42
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.42
POLB P06746 1/20 0.42
TYR P14679 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
GLRA3 O75311 1/20 0.41
GLRB P48167 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21753677 0.94 CA2 (0.57) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL510694 0.92 CA2 (0.59) CA2CA1CYP1A2CYP2C9CYP2C19
Benzene SCHEMBL29148570 0.90 CA2 (0.74) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL426214 0.90 CA2 (0.74) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL13840641 0.88 CA2 (0.71) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL13779478 0.87 CA2 (0.63) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL14344874 0.84 CYP1A2 (0.62) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL13840639 0.83 CYP1A2 (0.78) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL6346254 0.81 CRHBP (0.66) CA2CA1CYP1A2CYP2C9CYP2C19
SCHEMBL14557192 0.80 HSPA5 (0.56) CA2CA1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-2797938-B1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2016-06-01 EP disclosed
EP-2797938-A1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2014-11-05 EP disclosed
US-8841474-B2 Process for preparing 6-chlorodibenzo[D,F][1,3,2]dioxaphosphepin BASF SE (DE) 2014-09-23 US disclosed
US-20130172596-A1 PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2013-07-04 US disclosed
WO-2013098371-A1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2013-07-04 WO disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172596-A1 PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN DCPS, PLCB3, DDT CA2 826/4885CA1 535/4885CYP1A2 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.