SCHEMBL8990155

SCHEMBL8990155

CCCCCCCCCCCCc1cc(CC)cc(-c2cc(CC)cc(C(C)(C)C)c2O)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.55
PTGS2 P35354 7/20 0.40
ALOX5 P09917 5/20 0.40
CYP3A4 P08684 3/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
TP53 P04637 2/20 0.38
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
KDM4E B2RXH2 1/20 0.38
SHBG P04278 1/20 0.38
HSPD1 P10809 1/20 0.38
ADRB3 P13945 1/20 0.38
HTR2C P28335 1/20 0.38
HSPE1 P61604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6395831 0.92 HSPA5 (0.47) HSPA5PTGS2ALOX5CYP3A4ESR1
SCHEMBL15064834 0.85 PTGS2 (0.53) HSPA5PTGS2CYP3A4ESR1ADRA2A
SCHEMBL8990123 0.85 PTGS2 (0.53) HSPA5PTGS2CYP3A4ESR1ADRA2A
SCHEMBL11188772 0.85 PTGS2 (0.53) HSPA5PTGS2CYP3A4ESR1ADRA2A
SCHEMBL17781753 0.85 PTGS2 (0.53) HSPA5PTGS2CYP3A4ESR1ADRA2A
SCHEMBL1086409 0.84 HSPA5 (0.54) HSPA5PTGS2ALOX5CYP3A4ESR1
SCHEMBL8351586 0.84 HSPA5 (0.54) HSPA5PTGS2ALOX5CYP3A4ESR1
SCHEMBL15065758 0.84 PTGS2 (0.52) HSPA5PTGS2CYP3A4ESR1ADRA2A
SCHEMBL1151261 0.82 HSPA5 (0.51) HSPA5PTGS2ALOX5CYP3A4TP53
SCHEMBL8897086 0.82 HSPA5 (0.67) HSPA5CYP3A4TP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed