Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28452149 | 0.82 | ALOX5 (0.49) | OPRM1OPRL1OPRK1OPRD1ALOX5 | |
| SCHEMBL8990273 | 0.79 | GAA (0.42) | OPRM1OPRL1OPRK1OPRD1CHRNB2 | |
| SCHEMBL11462510 | 0.75 | CHRNB2 (0.41) | OPRM1OPRL1OPRK1CHRNB2SLC6A2 | |
| SCHEMBL13876257 | 0.74 | OPRM1 (0.59) | OPRM1OPRL1OPRK1OPRD1ALOX5 | |
| SCHEMBL15630944 | 0.72 | CHRNB2 (0.39) | CHRNB2SLC6A2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL8990373 | 0.72 | CHRNB2 (0.46) | OPRM1OPRL1OPRK1OPRD1CHRNB2 | |
| SCHEMBL10821867 | 0.71 | OPRM1 (0.56) | OPRM1OPRL1OPRK1OPRD1ALOX5 | |
| SCHEMBL14899046 | 0.71 | OPRM1 (0.56) | OPRM1OPRL1OPRK1OPRD1ALOX5 | |
| SCHEMBL13444795 | 0.71 | ALOX5 (0.54) | OPRM1OPRL1OPRK1OPRD1ALOX5 | |
| SCHEMBL13404297 | 0.70 | MEN1 (0.51) | OPRM1OPRK1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7133272-A | — | — | None | — | — | JP | disclosed |
| US-5500484-A | FROM ALDEHYDE | KURARAY CO., LTD. (JP) | 1996-03-19 | — | — | US | disclosed |
| JP-H07133272-A | 5-ALKOXY-5-ARYL-1,3-DIOXANE OR ITS DERIVATIVE AND PROUCTION THEREOF | KURARAY CO LTD | 1995-05-23 | — | — | JP | disclosed |
| EP-0641757-A1 | 2-Aryl-1,3-propanediol and dioxane derivatives and their preparation | KURARAY CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |