SCHEMBL8990291

SCHEMBL8990291

Cc1cc(C(C)(C)C2CCC(C)(c3cccc(C)c3Oc3ccc(N)cc3)CC2)ccc1Oc1ccc(N)cc1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
RAB9A P51151 2/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
RXRA P19793 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8973157 0.79 ALDH1A1 (0.41) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL8972892 0.75 MAOB (0.41) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL9100119 0.72 ALDH1A1 (0.32) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL29535518 0.68 ALDH1A1 (0.55) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL1856220 0.68 ALDH1A1 (0.55) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL29393830 0.68 ALDH1A1 (0.55) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL29363720 0.65 ALDH1A1 (0.56) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL1857666 0.65 ALDH1A1 (0.56) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL8762826 0.64 ALDH1A1 (0.54) ALDH1A1NPC1MAPTRAB9AHPGD
SCHEMBL16659204 0.64 TEAD4 (0.56) ALDH1A1NPC1MAPTRAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5489669-A FORMED FROM AMINE CONTAINING BIS/4-AMINOPHENOXY/PHENYL GROUPS; SOLUBILITY, DIELECTRICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-06 US disclosed
EP-0633282-A1 Polyimide and process for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-01-11 EP disclosed