Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990350 | 0.80 | OPRM1 (0.38) | IDO1SLC6A2SLC6A4 | |
| SCHEMBL8990452 | 0.79 | TSHR (0.43) | IDO1ALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL493225 | 0.75 | ALDH1A1 (0.40) | IDO1ALDH1A1KMT2ATSHRL3MBTL1 | |
| SCHEMBL9331587 | 0.73 | IDO1 (0.72) | IDO1KMT2AL3MBTL1 | |
| SCHEMBL23606754 | 0.73 | SMN1; SMN2 (0.46) | ALDH1A1KMT2ATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL643653 | 0.73 | OPRM1 (0.52) | ALDH1A1KMT2ATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL644234 | 0.72 | OPRM1 (0.48) | ALDH1A1KMT2ATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL10204155 | 0.70 | CACNA2D1 (0.49) | ALDH1A1KMT2ATSHRL3MBTL1SMN1; SMN2 | |
| SCHEMBL19129540 | 0.70 | IDO1 (0.62) | IDO1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14945167 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KMT2ATSHRL3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536725-A | Insecticidal substituted-2,4-diamino-5,6,7,8-tetrahydroquinazolines | FMC CORPORATION (US) | 1996-07-16 | — | — | US | disclosed |